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Sonic nebulizers are preferred because they minimize exposure of the agent to shear that can degrade the compound

Research suggests that ER stress is associated with various lesions during AS and affects the disease course, which occurs in endothelial cells, VSMCs, and macrophages by integrating protein and lipid metabolism, cell death, and inflammatory responses (69)

Non-enzymatic antioxidants Many nonenzymatic antioxidants are found in cells (e.g., GSH, uric acid, bilirubin, etc.) and a detailed discussion of this topic is beyond the scope of this chapter