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Coordinating replication with transcription

Numerous in vitro and in vivo studies have demon- strated the ability of melatonin to protect against free radical destructions [29,37,51,68,69]

Illustratively, the assessment included the morphologic features of mucosal injury (i.e., different grades of epithelial lifting, villi denudation, and necrosis), inflammation (i.e., focal to diffuse, according to lamina propria infiltration or subendothelial infiltration), and hyperemia/hemorrhage (i.e., focal to diffuse, according to lamina propria or subendothelial localization)