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B.umanS.MrgineanM.MihuC.IstrateM.et al (2018)

Neurology 87 , 168177 (2016)

Clinical combined risk scores further highlight that environmental exposures during early life have a greater impact on the age of IBD onset than genetic factors, emphasizing that the environment amplifies genetic risk through epigenetics, microbiota, and barrier signaling pathways, playing a dominant role in disease initiation [246]

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