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Occasionally, individuals experience temporary minor discomfort or sensitivity at injury sites during early treatment

D.Coppola, Moffitt Cancer Research Center, University of South Florida, Tampa, FL, USA for supporting the work on ascorbyl stearate in his laboratory

The mechanisms by which IGF-I reverses and/or prevents microvascular rarefaction and improves tissue blood supply are likely multifaceted, and may involve, among others: 1) Apoptosis, since IGF-I inhibits oxidative stress-induced apoptosis by preserving the functional integrity of the mitochondria[56, 290]

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