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McGeachy, M.J

Antioxidants 10 (7), 1057

Trerotola M, Cantanelli P, Guerra E, Tripaldi R, Aloisi AL, Bonasera V, et al

Thiol-based mucolytic agents, N-acetylcysteine (NAC), carbocisteine, and erdosteine, which act by breaking disulfide bonds in mucins, thereby lowering mucus viscosity and enhancing expectoration, modestly reduce exacerbation rates and hospitalizations in COPD, with the greatest benefit observed in patients with frequent exacerbations and a chronic bronchitis phenotype