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It also reduced neutrophil infiltration (myeloperoxidase activity), NF-B activation, and apoptosis-related proteins (Bax and Bcl-2), demonstrating its anti-inflammatory and protective effects in SCI

doi: 10.1159/000492120 17 HatzimouratidisKSaloniaAAdaikanGBuvatJCarrierSEl-MeliegyAet al

Further experiments showed that inactivation of the arachidonate 12-lipoxygenase (ALOX12) gene on human chromosome 17p13.1, located close to the p53 site, and knockout of an ALOX12 allele is sufficient to inhibit p53-mediated ferroptosis

It effectively removes the outermost layer of dead cells, revealing brighter and fresher skin