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On the other hand, accumulation of misfolded proteins per se was shown to directly inhibit the proteasome activity [78], exacerbating these toxic effects

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223,224,225,226 When mitochondrial dysfunction occurs, it often shows a decline in physical function and the occurrence of age-related diseases

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The fruit also contains some, but it's less potent

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Read source Yurko-Mauro, K., et al

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