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doi: 10.1016/j.copbio.2023.103011 117 LiHMaLLiWZhengBWangJChenSet al

22 Conditions such as aging, hypertension, ischemic heart disease, diabetes, and chronic lung disease are associated with decreased baseline GSH levels, while smoking, obesity, alcoholism, renal failure, cancers, and other chronic diseases are linked to disruptions in GSH homeostasis, impairing glutathione functionality

During single mitochondrial imaging experiments, single excitation HyPer7 intensities per mitochondrion were normalized to that same mitochondrions area in each frame, which similarly limited expression-based confounds