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Associations with polymorphisms in genes encoding UGT1A1, UGT1A6, UGT1A9, UGT2B15, and SULT1A1 were not detected in the same patient populations [100]

The ideal responder profile, while biologically coherent, was identified through post hoc subgroup exploration and is vulnerable to overfitting and multiple comparison artefacts

A randomized controlled study demonstrated that acupuncture combined with methylcobalamin is more effective in treating BIPN than methylcobalamin alone (Moore et al., 2020)