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20 Briefly, for all AI xenograft studies, NOD/SCID or NSG male mice (810 weeks old) were castrated on day 0

Escalate only after confirming tolerance and assessing initial response

Kanazawa M, et al

At the same time, GHRP-2 is believed to possibly inhibit the secretion of the appetite-reducing hormone, melanocyte-stimulating hormone (-MSH), thus shifting the equilibrium towards increased hunger and encouraging dietary intake