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Experts recommend precision nutrition strategies: Smaller, nutrient-dense meals rich in high-quality protein Micronutrient support for vitamins B12, D, folate, magnesium and iron Hydration solutions to counter reduced thirst signals Fiber and probiotics to support gut health GLP-1 therapies are revolutionizing obesity and diabetes care, but they also reshape physiology in ways that demand attention

The mechanistic rationale builds on earlier work by Kraus and colleagues in Nature (2014), in which adipocyte-specific NNMT knockdown protected mice from diet-induced obesity, establishing NNMT as a metabolic-disease target candidate [2]

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In contrast to WAT, interscapular BAT was larger in HSL null mice than in control