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Index Nominum 2000: International Drug Directory

The Lee 2016 work adds VEGF upregulation and TGF-beta-1 reduction as supporting mechanisms

Wolfe, F., Huser, W., Hassett, A

Interestingly, the inhibitor CPD-3B is virtually non-toxic to normal cells, while targeting not only GLS1 and GDH but also thioredoxin reductase (TrxR) and amidotransferase (GatCAB), resulting in the selective elimination of cancerous cells through a multifaceted mechanism