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Description

Neuregulin 4 downregulation in adipocytes induces insulin resistance through inflammation and autophagic degradation of GLUT4 vesicles (179)

An increased level of triglycerides is dangerous because it causes several heart diseases

We hypothesize that exposed hydrophobic core in PD-specific Syn variants not only drives aggregation and phase separation but also promotes promiscuous, non-functional binding to diverse proteins