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Dopaminergic therapies such as levodopa, dopamine agonists, and monoamine oxidase B (MAO-B) inhibitors provide meaningful relief, particularly during the early stages of the disease, but their efficacy wanes over time [5]

In Embodiment 70 of this disclosure are compounds of Formula or any one of Embodiments 1-69, or a pharmaceutically acceptable salt of any of the foregoing, wherein X and Y are C(R 5 )

C., Ferguson, K

Cells were treated with BSO in the presence or absence of the indicated inhibitor for 24 h to assess the modulating effect of the inhibitor on BSO-induced cytotoxicity