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The combination targets two complementary pathways: Cagrilintide activates amylin receptors (appetite suppression, delayed gastric emptying), while Semaglutide activates GLP-1 receptors (increased insulin secretion, appetite suppression, slowed gastric emptying)

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It may be helpful to think of these findings in terms of a pharmacological connectome that reflects the interactions of neurosteroids with various neural networks involved with the encoding and recall of memories