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doi: 10.1158/0008-5472.CAN-16-1979 70 LiuWDiJMaYWangSMengMYinYet al

A comprehensive single-cell atlas of the liver was constructed to profile the transcriptomic features of all cells in the liver tissues of healthy mice and those of the treatment group from day-0 (MSCs transplantation) to day-14

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As a result, fructose bypasses the key regulatory node in glycolysis, enabling a sustained and unregulated influx of carbon into glycolytic and lipogenic pathways, even under conditions that suppress glucose metabolism (30, 46, 48, 49)