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Ferroptosis has been shown to follow a different cell death pathway from apoptosis and thus is attracting attention as a new target for cancer therapy

N Engl J Med 290:13991402 Krauskopf J, Caiment F, Claessen SM, Johnson KJ, Warner RL, Schomaker SJ, Burt DA, Aubrecht J, Kleinjans JC (2015) Application of high-throughput sequencing to circulating microRNAs reveals novel biomarkers for drug-induced liver injury

Following long-term exposure to jet fuels, fatigue, dizziness, and/or sleep disturbances were more frequently reported by exposed Swedish aircraft mechanics compared to less heavily exposed or unexposed individuals

299 The pathogenesis of AD is often linked to insulin resistance, with PI3K playing a central role in insulin signaling, including GLUT translocation, glycogen synthesis, lipid and protein synthesis, anti-lipolytic effects, and hepatic gluconeogenesis