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The single biggest problem with this year is the extremely low elevation of the planet as viewed from mid-northern latitudes

Zhao L-P, Wang H-J, Hu D, Hu J-H, Guan Z-R, Yu L-H

Goyal et al., 2021)

For example, native chemical ligation (NCL) 12 , which is the most utilized approach for assembling the desired polypeptide sequence, relies on the presence of N-terminal Cys, -, - and -thiolated amino acids 1 , or a thiol modified auxiliary 13,14,15,16