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A 2 -test or unpaired t -test was used to test for statistically significant difference in response between patients with CD and UC, for difference in secondary parameters between responders and nonresponders (Table 1), and for haplotype analysis (Supplementary Tables 47)

Discrepant outcomes from earlier studies, largely attributable to small sample sizes and variations in primary endpoints and vitamin E formulations, have contributed to this cautious stance

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