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It has demonstrated to play a significant role in brain, heart, and gut repair, wound healing, bone, ligament and tendon injury

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It has been suggested that ferroptosis has a critical role in decreased viability of chondrocytes in OA, and here, we review recent findings regarding the pathologic pathways that lead to chondrocyte ferroptosis, and discuss the possible therapeutic utility of ferroptosis inhibition in OA

Our lipid class enrichment analysis revealed significant alterations following mrps-5 RNAi, particularly in triglycerides (TGs), which constituted the largest subset of enriched lipids (Fig