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The most evidence-backed approach is combining both their complementary mechanisms produce synergistic results exceeding either alone

Pinkston, and R.J

Cisplatin and DNA repair in cancer chemotherapy

In addition, xCT, the specific subunit of system x is upregulated in the vicinity of senile plaques, probably in microglia, in Thy1-APP 751 mice (TgAPP) expressing human APP bearing the Swedish (S: KM595/596NL) and London (L: V6421) mutations as well as after A injection in the hippocampus (Qin et al., 2006)