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Side Effects and Contraindications Common side effects of oxycodone include: constipation nausea sedation dizziness respiratory depression respiratory arrest hypotension fatal overdose Clinicians should withhold oxycodone from those who have an allergic reaction to opioids (hypersensitive), along with individuals experiencing a significant reduction in breathing rate and quality (respiratory depression), as well as bronchial asthma or having a temporary dysfunction of the intestines, which prevents food and waste from moving through the intestines (paralytic ileus) (56)

Bruising is technically not an injection site reaction in the same category as redness or itching, since it results from mechanical trauma rather than an immune response

Symptoms include numbness, tingling, walking problems, and memory loss