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doi: 10.1104/pp.109.139782 38 GoncalvesR

However, these in vivo approaches require careful design to balance throughput, ethical considerations, and translational relevance (e.g., dosing regimen, exposure duration), underscoring the need for integrated strategies that leverage both zebrafish and murine models (Xia et al., 2022

LD 50 values by the dermal route were not available

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