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A significant reduction in larval metabolic activity was observed for all three anthelmintics at different concentrations

doi:10.1097/MCO.0000000000000178

10 Similarly, in November 2022, FDA approved the combination of durvalumab, an anti-PD-L1 antibody, and tremelimumab, an anti-CTLA-4 (the cytotoxic T-lymphocyte-associated protein 4) antibody, which demonstrated remarkable therapeutic outcome in the HIMALAYA trial, achieving a 4-year OS rate of 25.2% for advanced HCC patients

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