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Contemp Clin Trials (2022) 122:106941

Nat Rev Immunol 21:83100 Price MJ, Patterson DG, Scharer CD, Boss JM (2018) Progressive upregulation of oxidative metabolism facilitates plasmablast differentiation to a T-independent antigen

Traumatic brain injuries destroy neural tissue resulting in impaired blood perfusion, excessive release of the neurotransmitter, glutamate (excitotoxicity), inflammation, and progressive secondary neuronal cell death