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In contrast, the centers of PSD-95 nanomodules were significantly closer to the centers of GluN1 subunit nanoclusters than to either GluA1 or GluA2 subunit clusters both on average and over the distribution (GluN1: 173.4 2.0 nm

Despite advancements in treatmentincluding chemotherapy, targeted therapy with epidermal growth factor receptor antibodies, and immunotherapy with immune checkpoint inhibitorsmany CRC cases exhibit intrinsic or acquired resistance to cancer treatment, leading to limited treatment efficacy and high recurrence rates