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The outcome of antipsychotic discontinuation would trigger a new treatment exposure period of no antipsychotic use in our study (i.e., 60-day period without any antipsychotic medication after the last antipsychotic prescriptions days supply was exhausted) and, indeed, these periods of no antipsychotic use were associated with a 11% to 32% higher risk of psychiatric hospitalization compared to periods with use of oral risperidone or other LAI reference groups

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Applying a cold compress to the injection site may alleviate local discomfort