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These complexes detect danger signals such as PAMPs and DAMPs, leading to the activation of caspase-1 and the maturation of pro-inflammatory cytokines IL-1 and IL-18

It's like, what's going on, man

Science 381 , 10921098 (2023)

Extrinsic regulation of oligodendrocyte responses OL responses are regulated by extrinsic influences throughout the lifespan, including in response to CNS injury