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Low levels of glutathione are linked to conditions such as Parkinsons disease and other neurodegenerative disorders

The homogenates were centrifuged at 10,000 g for 10 min at 4 C

Instead, it can be mimicked by agents that induce the unfolded protein response (UPR), a signal transduction pathway activated by the accumulation of unfolded proteins in the lumen of the endoplasmic reticulum (ER) [65]