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PMID: 106 Moreno-IndiasI.Snchez-AlcoholadoL.Prez-MartnezP.Andrs-LacuevaC.CardonaF.TinahonesF.et al

Applied and Environmental Microbiology, 72(7), 49504956

In this model, transient occlusion of the LAD coronary artery, typically around 3060 min, induces ischaemia, followed by reperfusion upon suture removal, activating common mechanisms underlying IRI, such as oxidative stress, calcium overload, mitochondrial dysfunction, and inflammatory responses, similar to human IRI [67]