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In the same trial, people on CagriSema lost an average of about 23% of their body weight over 68 weeks when measuring the effect assuming full adherence, or about 21% when accounting for all participants regardless of whether they completed treatment

A 2016 study involving healthy human volunteers and mice found that taking 1000 mg of NR supplements twice daily (totalling 2000 mg) had a steady-state NAD+ booster effect and also stimulated NAD+ metabolism