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however, it induced hypothermia and caused plasma melatonin to remain elevated into the daylight hours

A previous study reported significantly increased lipid peroxidation (measured by 4-HNE and MDA) in the synovial cells of OA than in RA patients and controls [46]

Cognitive dysfunction may also be associated with reduced neurosteroid levels, such as pregnenolone and allopregnanolone, highlighting a dysregulation of neuroendocrine pathways