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c IARC, International Agency for Research on Cancer

Regulation of TIMP-1 expression involves the activation of transcription factors including AP-1, Sp1, STAT, and Pea3/Ets families, as well as signaling pathways such as the ERK1/2 pathway [51]-[53]

Morever, immune cells such as T cells and innate lymphocytes, which have only recently been discovered, still require a great deal of research to demonstrate the role and mechanisms of UA in their regulation