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Double heavy isotope-labeled peptides guide the sensitive and selective acquisition of endogenous target spectra, and single heavy isotope-labeled peptides (hip) refolded into MHCs (hipMHCs) are used as embedded standards during peptide purification and processing for accurate copies-per-cell (CPC) quantification (Fig

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Xu W, Hu X, Anwaier A, Wang J, Liu W, Tian X, et al