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In addition, FADS2-mediated ferroptosis inhibited hepatitis C virus (HCV) replication, and triple-negative breast cancer cells with high FADS1/2 expression were found to be more susceptible to ferroptosis 76,79

In addition, deletion of Gclc increased glutamate levels in the liver and serum, but not the kidney (Figures 6B-D)

Greenlee KJ, Werb Z, Kheradmand F

The combined effects of decreased cellular ATP and elevated ROS production are most likely responsible for the initiation of cell death-related signaling pathways