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Defined in 1911 by psychiatrist Eugen Bleuler, who used the term Autism (Greek autos to describe extreme social withdrawal) to define a cluster of unique symptoms that were traditionally thought to be described as symptoms of schizophrenia (Landrum and Benham, 2018[25]

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Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor