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Ein niedriger Glutathionspiegel kann zu einer erhhten Anflligkeit fr Krankheiten und chronische Erkrankungen fhren

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These studies show that chronic usage of APAP at recommended therapeutic levels probably does mild liver damage and may be associated with a reduction in GSH levels that compromise antioxidant defense capacity

Previous studies have shown that SOD2 deficiency results in elevated oxidative stress, excessive ROS accumulation, impaired mitochondrial antioxidant defenses, and increased susceptibility to apoptosis ( In line with previous observations, our data demonstrated that HSYA treatment significantly increased SOD2 activity in the intestinal epithelial cells of septic mice