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We will reevaluate the APC assignment for CPT code 31647 in the next rulemaking cycle

This is notable because chronically elevated insulin has been proposed to promoted gain in adiposity and dysregulated glucose control (3840)

Interleukin-1 and tumor necrosis factor are essential in controlling an experimental orthopedic implant-associated infection

Funding The authors express their gratitude to Oswaldo Cruz Foundation of Pernambuco (FIOCRUZ-PE), Research Excellence Program - Aggeu Magalhes Institute (IAM PROEP#400208/2019-9), Knowledge Generation Program Oswaldo Cruz Foundation (FIOCRUZ