Goal: Reduce visceral adipose tissue and improve lipid profiles through sustained GH/IGF-1 elevation [3] [4]
Data were assumed to be normally distributed
Meanwhile, increased angiopoietin-2 levels were also observed in individuals with overweight and obesity compared to lean control subjects (300, 330), further indicating the potential involvement of angiopoietin-2 in obesity-induced vascular remodeling
In addition, they can also assist in the prevention and treatment of thyroid immune diseases by activating natural killer (NK) cells ( Scrophularia Radix ceae polysaccharides also have antifatigue effects and can improve the symptoms of fatigue and weakness caused by metabolic disorders in patients with thyroid diseases and diabetes ( 2.1.7 Flavonoids Flavonoids are widely present in nature and have various biological activities, such as liver protection, antitumor, and antioxidant effects ( 2.1.8 Alkaloids Alkaloids in Scrophulariae Radix , such as genipin, act mainly on the nervous system and have sedative, antidepressant and antianxiety effects ( 2.1.9 Phenols Phenolic compounds such as chlorogenic acid have antioxidant, anti-inflammatory, and antibacterial effects ( 3 Pharmacological effects Studies on Scrophulariae Radix have highlighted its anti-inflammatory, antioxidant, immunomodulatory, cardiovascular protective, and antitumor effects ( 3.1 Anti-inflammatory effects Key components of Scrophulariae Radix , including iridoid glycosides such as aucubin and geniposide, show strong anti-inflammatory activity ( 3.2 Antioxidant effects Flavonoids in Scrophulariae Radix help neutralize reactive oxygen species (ROS), protecting cells from oxidative stress ( 3.3 Immunomodulatory effects Polysaccharides from Scrophulariae Radix increase immune responses by stimulating macrophage and lymphocyte activity ( 3.4 Cardiovascular protection Scrophulariae Radix has shown notable cardioprotective effects in various studies ( 3.5 Antitumor effects Polysaccharides from Scrophularia ningpoensis significantly increase the thymus and spleen indices and prolonge survival in S180 tumor-bearing mice ( S
