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[27] Findings beginning in 1999 and later revealed a previously unrecognized layer of biology: these proteins control gene expression within the cell of origin, and when released exert homeostatic and developmental control in specific human cell types, tissues and organs during adult or fetal development or both, including pathways associated with angiogenesis, inflammation, the immune response, the mechanistic target of rapamycin (mTOR) signalling, apoptosis, tumorigenesis, and interferon gamma (IFN-) and p53 signalling

Magnesium and the inflammatory response: potential physiopathological implications

10.1093/jxb/err245 101 XueX

Results Zonulin expression correlates with onset of rheumatoid arthritis The permeability and barrier function of the intestinal epithelium depends on the regulation of intercellular TJ