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Serum B12 Test - Standard blood test measuring overall B12 levels Methylmalonic Acid (MMA) Test - Indicates functional B12 status Homocysteine Test - Helps confirm B12 deficiency Holotranscobalamin (HoloTC) Test - Measures active B12 Healthcare providers may recommend: Baseline Testing: Complete assessment before starting Wegovy Initial Phase: B12 checks every three to six months Maintenance Phase: Annual testing once levels stabilize Most insurance plans may cover B12 testing when medically necessary, particularly for patients using medications that may affect absorption