he effects of stress and aging on glutathione metabolism Frontiers Changes in levels of the

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Iron deficiency and iron overload are considered important causes of chronic metabolic diseases (such as T2DM or obesity) [108] Studies have shown that mice fed with rich iron diets showed upregulation of IR-related adipokines because an iron-enriched diet induces insulin resistance and hypertriglyceridemia and affects visceral adipose tissue metabolism by a mechanism involving hepcidin up-regulation [109]

Ridder et al

In theory, combining these compounds may support complementary cellular pathways involved in energy metabolism, antioxidant defense, and detoxification