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Additionally,certain medications that many patients take before and after surgery can decrease vitamin B 12 absorption and stores in the body

If you feel low on energy (fatigue), even when eating enough, semaglutide with B12 might help prevent this feeling of not having enough energy to carry out your routine tasks or workout

However, weight loss from GLP-1 therapy can improve insulin sensitivity and reduce blood sugar levels, which may require adjustments to diabetes medications such as insulin or sulfonylureas

Patients undergoing treatment with chemotherapy agents, particularly those known as antifolates (e.g., methotrexate), should use methylcobalamin with caution