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Implantation of rAAV5-IGF-I transduced autologous chondrocytes improves cartilage repair in full-thickness defects in the equine model

Additionally, patients with CD have lower levels of antioxidative substances such as plasma ascorbic acid, - and -carotene, lycopene, and -cryptoxanthin, as well as tissue GSH, which takes part in GPx-catalyzed H 2 O 2 reduction (161)

Loss of myelin basic protein function triggers myelin breakdown in models of demyelinating diseases

Conversely, declining ghrelin concentrations reduce insulin sensitivity and impair pancreatic -cell function, diminishing insulin secretion and glucose regulation