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Furthermore, overexpression of RCAN1.4 promotes the apoptosis of activated HSCs, both in vitro and in vivo , and also attenuates liver fibrosis

The proposed mechanism is two-fold: transplanted mitochondria can directly supply ATP to energy-starved cells and can also modulate immune cells by reducing DAMPs release and apoptosis

When Lowry left, Siakam emerged as Toronto's perennial star, earning two NBA All-Star nods before being traded to the Indiana Pacers during the 2023-24 season in a package that included multiple first-round picks