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Allergen-induced substance P synthesis in large-diameter sensory neurons innervating the lungs

Unlike most water-soluble vitamins, B12 requires stomach acid to separate it from food, a protein called intrinsic factor to carry it, and a healthy ileum (the end of the small intestine) to absorb it

The FDA says that they would not take action against a compounder for using a Category 1 substance but would consider taking action for those that use Category 2 or 3 substances

While a two-year clinical trial using 300 mg per day did not show major changes in nerve function, shorter studies lasting 3 to 12 weeks found that higher doses, up to 600 mg daily, improved symptoms in people with diabetic neuropathy