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FGF21 also increases energy expenditure in mice via UCP1-dependent (232) and UCP1-independent (233) mechanisms, which include browning of white adipose tissue by upregulating PGC1 (234)

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A randomized, placebo-controlled trial investigating the acute and chronic benefits of American Ginseng (Cereboost) on mood and cognition in healthy young adults, including in vitro investigation of gut microbiota changes as a possible mechanism of action