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In a tightly controlled feedback loop, progesterone then limits expression of ER-alpha via PR-A (McDonnell and Goldman, 1994)

Zebrafish disease models in drug discovery: from preclinical modelling to clinical trials

Foxo3 is required for the regulation of oxidative stress in erythropoiesis

A plausible explanation could be a reorientation of Lys105 towards GS resulting in a decreased stabilization of the active site thiolate as a leaving group