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The brain also influences kidney function through several key pathways, primarily involving neural, metabolic, and hemodynamic mechanisms, including the SNS, RAAS, HPA axis, and neural circuits and associated feedback loops (Freeman and Wadei, 2015

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2.3 Study selection and data extraction After completing the initial database searches, all retrieved records were screened by title and abstract to identify potentially relevant studies, followed by a full-text review to determine final eligibility based on the predefined inclusion and exclusion criteria

Third, as detailed in Table 1, anti-AFs properties of PPs are not generally focused on specific pathways, though the majority of studies confirmed that these metabolites function through suppressing of AFs-induced oxidative stress