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M.CliftonG

DNA Methyltransferase Inhibitors Upregulate CD38 Protein Expression and Enhance Daratumumab Efficacy in Multiple Myeloma

In murine models, NNMT knockdown did not induce the accumulation of NAM in livers and adipose tissues, nor did it cause significant alterations in the intracellular levels of NAD + in hepatocytes (Kraus et al., 2014